New article published: Lobet et al, 2025
𝐇𝐞𝐦𝐨𝐩𝐡𝐢𝐥𝐢𝐜 𝐚𝐫𝐭𝐡𝐫𝐨𝐩𝐚𝐭𝐡𝐲 is one of the common complications of hemophilia and results from 𝐫𝐞𝐩𝐞𝐚𝐭𝐞𝐝 𝐡𝐞𝐦𝐚𝐫𝐭𝐡𝐫𝐨𝐬𝐢𝐬 in a joint. It causes epiphyseal hypertrophy, decreased joint range of motion, muscle atrophy, and muscle-tendon retractions. The joints most commonly affected are the 𝐤𝐧𝐞𝐞𝐬, 𝐚𝐧𝐤𝐥𝐞𝐬, 𝐚𝐧𝐝 𝐞𝐥𝐛𝐨𝐰𝐬. It has a major impact on patients' quality of life. Hemophilic arthropathy is assessed using X-rays, magnetic resonance imaging, and joint ultrasound. The authors published a narrative review with the aim of establishing an 𝐨𝐯𝐞𝐫𝐯𝐢𝐞𝐰 𝐨𝐟 𝐭𝐡𝐞 𝐥𝐢𝐭𝐞𝐫𝐚𝐭𝐮𝐫𝐞 𝐨𝐧 𝐇𝐄𝐀 𝐢𝐧 𝟐𝟎𝟐𝟓.
After reviewing 45 articles, the authors concluded that HEA is a condition that significantly 𝐚𝐟𝐟𝐞𝐜𝐭𝐬 𝐭𝐡𝐞 𝐪𝐮𝐚𝐥𝐢𝐭𝐲 𝐨𝐟 𝐥𝐢𝐟𝐞 of patients with hemophilia, with an 𝐢𝐧𝐬𝐢𝐝𝐢𝐨𝐮𝐬 𝐨𝐧𝐬𝐞𝐭 due to the body's ability to compensate for damage in the early stages. However, the delay in treating this complication often means that it is too late, as the joints are 𝐚𝐥𝐫𝐞𝐚𝐝𝐲 𝐢𝐫𝐫𝐞𝐯𝐞𝐫𝐬𝐢𝐛𝐥𝐲 𝐝𝐚𝐦𝐚𝐠𝐞𝐝. The progression of HEA can be slowed by targeted physical therapy, with surgery only considered in advanced cases and as a last resort.
Advances in the early detection and management of HEA in patients with hemophilia 𝐨𝐩𝐞𝐧 𝐮𝐩 𝐧𝐞𝐰 𝐩𝐫𝐨𝐬𝐩𝐞𝐜𝐭𝐬 for improving the management and prevention of irreversible joint damage. The article is available on the journal's website. Doi: 𝟏𝟎.𝟏𝟏𝟏𝟏/𝐡𝐚𝐞.𝟕𝟎𝟏𝟕𝟖.